Immune Thrombocytopenia (Itp) In Emergency Medicine

Immune Thrombocytopenia (ITP) is an autoimmune disorder characterised by a low platelet countless than 100? ×? 10^9/L, purpura, and hemorrhagic episodes induced antiplatelet autoantibodies without anemia or leukopenia. thrombocytopenia occurs in 2 to 4/100? 000 adults. A wide range of signs symptoms, from modest mucocutaneous petechiae severe, life-threatening organ haemorrhage, are seen ITP patients. they may present the emergency department (ED) with bleeding as result their thrombocytopenia. has two distinct clinical syndromes, manifesting acute condition children chronic IgG make circulating platelets more sensitive. It causes these cells be removed quickly antigen-presenting (macrophages) spleen, occasionally liver other components monocyte-macrophage system. Current evidence supports alternatives splenectomy for second-line management patients persistently counts bleeding. By increasing production, bone marrow compensates breakdown. most commonly arises within few weeks after viral infection healthy young Immunosuppressive treatment usually effective treating ITP. Many require no emergent treatment. However, physician should start transfusion, corticosteroids, intravenous immune globulin (IVIG) soon patient suspected arrives at ED serious haemorrhage.The diagnosis made ruling out all known This review aims summarize current evidences regarding prevalence, causes, Keywords:,,,